Membrane Heat Shock Protein 70 (mHsp70): a cancer biomarker discovered to be highly expressed on the cell membrane of many liquid and solid tumors, but not on healthy cells.
Metastases (the major cause of death by cancer) express even higher amounts of mHsp70 than primary tumors.
Tumors expressing membrane Hsp70 release exosomes, levels of which reflect tumor size, therapeutic response and disease recurrence.
RB-203: Novel proprietary monoclonal antibody recognizing membrane Hsp70 selectively accumulates in tumors expressing membrane Hsp70, but not in healthy cells.
Companion Diagnostic: Patented blood test for detecting the presence of tumors expressing membrane Hsp70 as well as monitoring therapeutic response and disease recurrence.